Oral ranula (10)iRecurred after 3 surgeriesj


Left: Before treatment, Right: After Treatment

Fourties man. This case was very difficult to diagnose and treat. He had already 3 surgeries for 2 and a half years before he came to my clinic. He complained small right oral floor swelling.


From Left: Before treatment, The next day after treatment, 1 week after treatment, 6 weeks after treatment

This is the first time OK-432 therapy. At first, I thought that it was very small ranula. I injected 0.5 KE of OK-432 in 0.2 ml saline in it. The next day, his oral floor was diffusely swollen. This means that ranula is bigger than I expected. This treatment was not effective.


From Left: Before treatment, The next day after treatment, 8 weeks after treatment

So, I checked MRI. White lesion is fluid collection. Ranula was existed along with inside of submandibular bone and deep in oral floor. Ranula I could see from mouth was a very limited part of ranla. Because I knew ranula was big, I injected 1 KE. But, it was not effective.


From Left: Before treatment, The next day, 1 week after, 8 weeks after, 1 year after treatment

This is the third treatment. As the third treatment, 1 KE of OK-432 was injected. This time, ranula was disappeared. After one year of treatment, there was no recurrence. I think MRI is very important for the patient who had surgery before.

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